The Relationship Between Proteinuria and Urine Specific Gravity in Diabetes Mellitus Patients at Santa Elisabeth Hospital, Medan
DOI:
https://doi.org/10.37012/jik.v18i2.3815Keywords:
Diabetes Mellitus, Proteinuria, Urine Specific GravityAbstract
Uncontrolled blood sugar levels over an extended period can lead to various chronic complications in patients with diabetes mellitus, one of which is diabetic nephropathy. Diabetic nephropathy is characterized by damage to the glomerular filtration membrane, which can result in increased protein excretion in the urine (proteinuria). The presence of protein in the urine can influence urine specific gravity, as protein is a solute that contributes to urine concentration. This study aimed to determine the relationship between proteinuria and urine specific gravity in patients with diabetes mellitus. A descriptive-analytic correlational method with a cross-sectional approach was employed. The study sample consisted of 19 patients with diabetes mellitus selected using an accidental sampling technique. Proteinuria and urine specific gravity were measured using an automated Mindray UA-600 T Urine Analyzer. Data analysis was performed using the Spearman Rank correlation test. Proteinuria test results showed 8 negative samples, 5 samples with a +1 result, 3 samples with a +2 result, and 3 samples with a +3 result. Urine specific gravity values ranged from 1.005 to 1.030. The analysis revealed a strong and significant relationship between proteinuria and urine specific gravity, with a correlation coefficient (r) of 0.745 and a p-value of 0.000 (p<0.05). This positive relationship indicates that an increase in proteinuria levels is accompanied by an increase in urine specific gravity values. However, this relationship does not imply causation, as the study utilized a cross-sectional design.
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Copyright (c) 2026 Leni Versi Laia, Paska Ramawati Situmorang, Rica Vera Br Tarigan, David Sumanto Napitupulu
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